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Synthetic CBD Vs Natural CBD: Let’s Compare

Written By

Nishant Garund

Medically Reviewed by Dr. Varuni Agarwal

Dr. Varuni Agarwal is an esteemed Ayurvedic physician specializing in diagnosing diseases through Ayurvedic dosha imbalances and providing personalized treatments. She focuses on ahara (diet) and vihara (lifestyle) to manage and heal various ailments.

Synthetic CBD Vs Natural CBD: Let’s Compare

In a time where health and wellness are more important than ever, CBD’s potential seems boundless. In recent times, CBD has gained the attention of many people seeking relief for many common health issues. But with its skyrocketing popularity, an important question arises: Is your CBD natural or synthetic? Both forms offer unique benefits, and understanding the difference can help you make the best choice that best fits your lifestyle and wellness goals. Whether you’re curious about the entourage effect of natural CBD or the purity and consistency of synthetic CBD, this blog will guide you through it all. Let’s uncover the fascinating world of CBD and hemp, the primary source of natural CBD, and empower you to make informed choices for your well-being. Keep reading to learn more!

Hemp: A Natural Powerhouse

Hemp (Cannabis sativa) is a naturally occurring plant cultivated for many years for its versatile uses.

Hemp (Cannabis sativa) is a naturally occurring plant cultivated for many years for its versatile uses. Unlike synthetic materials, hemp is natural, growing as a hardy crop that requires minimal pesticides and fertilisers. It has a rich history of being used in textiles, rope, paper, food, and wellness products. The plant is also a primary source of natural CBD and contains low levels of THC, the psychoactive compound found in marijuana. Hemp’s fibres, seeds, and extracts are all derived directly from the plant, making it an eco-friendly, sustainable resource. While innovations have led to synthetic alternatives that mimic some properties of hemp, the plant itself remains purely natural. Let’s look at some of the common facts about hemp: 

  • Entirely Natural: Hemp is a naturally occurring variety of Cannabis sativa, cultivated for its fibre, seeds, and extracts.
  • Low THC Content: Unlike marijuana, hemp typically contains less than 0.3% THC, making it non-psychoactive.
  • Versatile Uses: Hemp is used for producing textiles, paper, biodegradable plastics, food products, cosmetics, and CBD oil.
  • Eco-Friendly Crop: Hemp grows rapidly, requires little water, and improves soil quality, making it a sustainable crop.
  • Legal Distinctions: Many regions differentiate hemp from marijuana based on THC content, allowing for its legal cultivation.
  • Nutritional Benefits: Hemp seeds are a rich source of protein, omega-3, omega-6, and essential vitamins and minerals.
  • Ancient History: Hemp has been cultivated for over 10,000 years, historically used in China, Mesopotamia, and Egypt. 
  • Biodegradable Fibres: Hemp fibres are stronger and more durable than cotton and are naturally resistant to pests.

Exploring the World of CBD: Nature’s Miracle or Lab Innovation?

Cannabidiol, widely known as CBD, is a compound that originates from the Cannabis sativa plant. While often mistaken for synthetic due to its popularity in wellness products, CBD in its most common form is natural. Extracted from hemp and a variety of cannabis, CBD is non-psychoactive and praised for its potential therapeutic benefits. However, there is a synthetic version of CBD used in some pharmaceutical applications. This duality between natural and synthetic forms makes CBD a fascinating compound in modern health discussions.

  • Natural Origin: Most commercial CBD is extracted from hemp plants through CO2 extraction or ethanol methods.
  • Synthetic CBD: Some pharmaceutical-grade CBD products use lab-created CBD to ensure purity and consistency.
  • Non-Psychoactive: Unlike THC, CBD doesn’t produce a "high," making it appealing for medicinal and wellness use.
  • Therapeutic Potential: Research suggests CBD may help with anxiety, inflammation, pain, and sleep disorders.
  • Legal Complexity: Natural CBD’s legality varies by region, while synthetic CBD can sometimes bypass restrictions.
  • FDA-Approved Drug: Epidiolex, a synthetic CBD medication, treats severe epilepsy, showcasing its medical potential.

Whether sourced from nature or created in a lab, CBD continues to intrigue scientists, medical professionals, and wellness enthusiasts alike.

Differences Between Natural and Synthetic CBD

CBD, or cannabidiol, is a compound extracted from cannabis sativa. CBD serves numerous purposes in the health and lifestyle of an individual. CBD alleviates many health issues, both mental and physical. Synthetic CBD is produced from chemical synthesis or biological synthesis. Ingredients such as limonene, modified yeast, or bacteria are used in the production of synthetic CBD.

Although the production methods of natural and synthetic CBD are completely different, this does not affect their chemical composition. Natural and synthetic CBD are almost chemically similar.

Naturally produced CBD contains compounds such as terpenes, cannabinoids, and flavonoids. Synthetically produced CBD is made in labs to contain pure CBD molecules. Let’s discuss in detail the usage and application of both differently produced CBDs.

Natural vs. Synthetic CBD: Usage and Application

Are you in a dilemma about choosing the type of CBD that fits best with your needs? This blog is here to sort it out. The usage and application of CBD depend on various factors, such as the type of product, the needs of the user, etc.

Naturally produced CBD is generally expensive to manufacture. But the naturally occurring compounds such as terpenes, flavonoids, and cannabinoids, along with CBD, all together create an entourage effect. It is the main reason for the popularity of naturally sourced CBD.

For an increased yield of CBD, manufacturers may opt for synthetic CBD, as it is cheaper to produce. Also, synthetic methods may be chosen for a consistent production of CBD because synthetic CBD is made in labs and it becomes easy to maintain consistency in CBD compounds.

Synthetic CBD vs Natural CBD: The Entourage Effect

CBD, along with other naturally occurring compounds such as terpenes, cannabinoids, and flavonoids, creates the entourage effect.

Naturally derived CBD has these other naturally occurring compounds along with CBD. That’s why natural CBD is popular for creating the entourage effect.

Synthetic CBD contains pure CBD molecules and lacks all the other compounds. Thus, synthetic CBD cannot create an entourage effect.

Organic vs Synthetic CBD: Side Effects

The chemical composition of both natural and synthetic CBD is similar. The effects of both of them are also almost similar.

The chemical composition of both natural and synthetic CBD is similar. The effects of both of them are also almost similar. An individual may experience natural or synthetic CBD side effects when taken, depending on various factors like dosage, type of CBD, preliminary health condition, etc. It varies from person to person. It is not always sure whether CBD will cause side effects in a person or not.

Conclusion

While natural and synthetic CBD may sound different, they are almost similar in terms of chemical composition, benefits, and side effects. The factors where these differ from each other are production method, usage and application, and production efficiency. Synthetic CBD is cost-effective and consistent to produce. It contains pure CBD molecules with no other naturally occurring compounds. Naturally produced CBD is popular for creating the entourage effect because all the naturally occurring compounds, such as terpenes, cannabinoids, and flavonoids, along with CBD, are present in it. Both natural and synthetic CBD have different uses. Therefore, it depends on the needs and usage of the person, which may vary from person to person. However, it is always advisable to consult a medical professional before choosing or taking any kind of medication.

Frequently Asked Questions

What type of CBD creates the entourage effect?

Naturally derived CBD has other naturally occurring compounds such as cannabinoids, terpenes, and flavonoids. Together, these compounds create the entourage effect. Synthetic CBD lacks the other compounds. Thus, synthetic CBD cannot create an entourage effect.

How do I know if CBD is synthetic?

Natural CBD is derived from plants, whereas synthetic CBD is produced in labs. Checking the ingredients or reading the product label may help.

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