Understanding Smoking Cessation Side Effects: What to Expect When You Quit

Written by Nishant Garund
Medically Reviewed by Dr.Varuni Agarwal

Dr. Varuni Agarwal is an esteemed Ayurvedic physician specializing in
diagnosing diseases through Ayurvedic dosha imbalances and providing personalized treatments. She focuses on ahara (diet) and vihara (lifestyle) to manage and heal various ailments.

Understanding Smoking Cessation Side Effects: What to Expect When You Quit

Quitting smoking is one of the best decisions you can make for your health. However, it's important to be aware of the potential side effects of smoking cessation, which are often caused by nicotine withdrawal. Smoking cessation side effects are usually temporary and manageable, and the long-term health benefits of quitting far outweigh any short-term discomfort.

Objectives of Smoking Cessation

  •   Improved overall health

  •   Reduced risk of cancer, heart disease, stroke, and lung disease

  •  Increased lung function

  •  Improved sense of taste and smell

  •  Boosted energy levels

  •  Stronger immune system

Smoking Cessation Side Effects 

Many people struggle to quit smoking, and there's a scientific reason why. Nicotine, the main psychoactive compound in tobacco, is highly addictive. While its effects may not be as intense as illegal drugs like cocaine or heroin, nicotine's hold on the brain is just as strong.

This addiction is evident in nicotine withdrawal symptoms. The body's dependence on nicotine makes quitting a challenge, often leading to multiple attempts before success. Nicotine's influence goes beyond just psychological dependence. It impacts various bodily functions, including the heart, blood vessels, hormones, metabolism, and the brain itself. When deprived of nicotine, the body experiences withdrawal, characterized by intense cravings and irritability.

Physical Side Effects

  1. Cravings and Appetite Changes: Quitting smoking can lead to a surge in appetite within a few days. This is because nicotine influences receptors in the brain that regulate the release of serotonin and dopamine, chemicals that suppress hunger. Without the regular nicotine dose, these chemicals decrease, leading to increased appetite. Additionally, some people subconsciously replace smoking with snacking to manage cravings. This, along with potential cravings for sugary or high-carbohydrate foods, can contribute to weight gain in the initial quit attempt. The first two weeks are typically the most challenging, with an average weight gain of 5-10 pounds.

  2. Respiratory Issues: Nicotine impairs the body's natural ability to clear mucus and irritants from the lungs. During withdrawal, you might experience a cough as your respiratory system recovers. This cough can last for several weeks.

  3. Headaches and Dizziness: These are typically mild and often the first withdrawal symptoms to appear. Fortunately, they are also among the first to subside.

  4. Fatigue and Sleep Disruption: Nicotine acts as a stimulant, boosting alertness. Without this stimulation, you might feel more tired. However, this fatigue can be accompanied by restlessness and difficulty falling asleep (insomnia). 

dizziness caused by smoking

Changes in Mood and Emotional State:


Quitting smoking can disrupt your emotional well-being. Nicotine is often used to manage stress, so its absence can lead to increased anxiety. This typically starts around the third day of withdrawal and may persist for a few weeks.


Depression is another potential emotional consequence, sometimes starting as early as the first day but usually subsiding within a month. However, individuals with a history of anxiety or depression might experience more prolonged symptoms and may require additional support from a healthcare provider.

Increased Irritability

Quitting smoking can make you more prone to frustration and anger, especially as you navigate the physical withdrawal symptoms. This is a normal consequence and should subside over time.

Difficulty Concentrating

Nicotine withdrawal can temporarily impair your ability to focus and concentrate. This is likely due to the body adjusting to the absence of the stimulant effects of nicotine.

Smoking Cessation Guidelines: Taking Control of Your Health

Quitting smoking is one of the most important decisions you can make for your health. It can significantly improve your quality of life and reduce your risk of developing serious health conditions like cancer, heart disease, and stroke. However, quitting can also come with challenges, including experiencing smoking cessation side effects. Here are some detailed guidelines to help you navigate your smoke-free journey:

  1. Prepare for Your Quit Date:

  • Set a quit date: Choose a date shortly (ideally within 2 weeks) and commit to quitting smoking completely on that day.

  • Tell your loved ones: Enlist the support of your family, friends, and colleagues. Inform them about your quit date and ask them to hold you accountable.

  • Cleanse your environment: Remove all cigarettes, lighters, and ashtrays from your home, workplace, and car. This minimizes temptation and reinforces your commitment.

  • Identify your triggers: Recognize situations or emotions that make you crave a cigarette. Plan alternative coping mechanisms like taking a walk, chewing gum, or deep breathing exercises.

  • Stock up on helpful resources: Consider nicotine replacement therapy (NRT) like patches, gum, or lozenges, which can help manage withdrawal symptoms. Explore online resources, support groups, or smoking cessation apps for additional guidance and motivation.

  1. Manage Withdrawal Symptoms and Stay Motivated:
  • Nicotine Replacement Therapy (NRT): NRT can be a valuable tool in managing withdrawal symptoms. Patches, gum, lozenges, and inhalers provide a controlled dose of nicotine, helping to reduce cravings and irritability. Consult your doctor to determine the best NRT option for you.
  • Focus on the Benefits: Remind yourself of the reasons you decided to quit. Make a list of the health improvements you can expect, both in the short and long term.
  • Develop Healthy Coping Mechanisms: Identify activities that help you manage stress and cravings without resorting to cigarettes. This could include exercise, spending time in nature, listening to music, or practising relaxation techniques like deep breathing or meditation.
  • Seek Support: Don't hesitate to seek support from your doctor, counsellor, or a smoking cessation program. They can provide resources, guidance, and encouragement throughout your quit journey.
  • Reward Yourself: Celebrate your milestones, no matter how big or small. Acknowledge your progress and reward yourself for sticking to your commitment. Remember, quitting smoking is a significant achievement.
  1. Relapse Prevention: Even with the best planning, there's always a chance of slipping up. If you do have a cigarette, don't beat yourself up. View it as a learning experience and recommit to your quit attempt. Here are some tips to prevent relapse:
  • Identify your triggers: Recognize situations or emotions that led you to have a cigarette. Develop a plan to cope with these triggers in the future.
  • Don't keep "just one" cigarette: Having even one cigarette can reignite your addiction.
  • Seek support immediately: Talk to a trusted friend, family member, or your doctor. 
say no to smoking


In conclusion, smoking cessation side effects are temporary hurdles on the path to a smoke-free future. While cravings, fatigue, and irritability can be disruptive, understanding these symptoms and having a plan to manage them empowers you to overcome them. Remember, the long-term health benefits of quitting far outweigh the short-term discomforts. Embrace the support systems available, celebrate your victories, and never give up on your smoke-free journey. With dedication and the right tools, you can successfully navigate smoking cessation side effects and achieve a healthier, happier you.

Frequently Asked Questions 

Q. What are the most common smoking cessation side effects?

Cravings are the most frequent side effect. You might also experience fatigue, irritability, difficulty concentrating, cough, headaches, and changes in appetite.

Q. How long do smoking cessation side effects last?

The intensity and duration of side effects vary depending on the individual. Most physical symptoms like cravings, fatigue, and headaches peak within a few days or weeks and gradually subside within a month or two. However, some people might experience lingering effects for a longer period.

Q. Is weight gain a common smoking cessation side effect?

Yes, some people experience increased appetite and cravings for sugary or high-carbohydrate foods, which can lead to weight gain. However, this weight gain is usually modest (5-10 pounds) and can be managed through healthy eating habits and exercise. Remember, the long-term health benefits of quitting smoking far outweigh the potential for weight gain.